Biometrics Team Leader/Senior Director - Global Medical Affairs/Payer Biometrics
Company: AstraZeneca
Location: Wilmington
Posted on: August 5, 2022
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Job Description:
Biometrics Team Leader/Senior Director - Global Medical
Affairs/Payer Biometrics Locations: Cambridge or Macclesfield (UK);
Gaithersburg or Wilmington (Delaware) (US); Warsaw (PO) or
Mississauga (CA) Competitive salary and benefits package on offer
Do you have a passion for science, statistics and leadership? Are
you up for the challenge to impact a company that follows the
science and turns ideas into life changing medicines? If yes, we
welcome you to join AstraZeneca At AstraZeneca, we put patients
first and strive to meet their unmet needs worldwide, while
applying leading edge approaches to science across many business
areas. Working here means being entrepreneurial, thinking big and
working together to make the impossible a reality. If you are swift
to act, confident to lead, willing to collaborate, and curious
about what science can do, then you're our kind of person. We are
currently looking for a Biometrics Team Leader/Director to lead,
manage and develop a group of statisticians who work within our
Global Medical Affairs (GMA) and Payer Biometrics statistics group
which sits within Oncology Biometrics. The Biometrics Team
Leader/Director reports to the Head of GMA/Payer Biostatistics and
is accountable for operational planning and delivery of services to
the groups two key stakeholders, GMA and Oncology Market Access and
Pricing (OMAP). For GMA, the group provides statistical support for
interventional and Real World Evidence (RWE) studies, including
developing design options and providing high quality decision
support. For OMAP, the group provides statistical support for the
Global Oncology Payer Function via the application of quantitative
skills to support decision-making processes and value
demonstration, including contributing to Health Technology
Assessment (HTA) submissions. What you will do: The main duties and
responsibilities of the role will include; To lead, manage and
develop a group of statisticians, ensuring the successful delivery
of projects while simultaneously considering the development needs
of statisticians. Efficiently utilize resource in the group and
beyond to deliver key projects to time, quality and within resource
constraints. Design and analysis of interventional and
non-interventional studies (incl. sample size estimation and
randomisation specification.) Developing statistical analysis plans
for complex studies and/or project deliveries. Contributing to
protocols, clinical study reports, regulatory documents and
manuscripts. Providing support to the payer function for late stage
oncology assets. Including post hoc analysis of clinical trial data
to support development of cost effectiveness and budget impact
models. Representing AstraZeneca to Health Authorities and
Reimbursement & Payer Organizations for specific projects Analysis
of published literature and RWE sources (e.g. network meta-analysis
and synthetic control arms). Dependent on experience, mentoring of
more junior staff and presenting at internal training seminars.
Desirable qualifications and experience: MSc or Ph.D. Statistics,
Biostatistics, or Mathematics (containing a substantial
mathematical component). Experience in drug development, study
design, and data analysis and interpretation. Experience of leading
projects and people in a pharmaceutical or CRO environment.
Publication experience and/or experience of presenting at external
meetings (e.g. ISPOR, PSI) Programming expertise in R, WinBugs
and/or SAS. Experience of reimbursement submissions in key markets
(e.g. UK and Germany.). Regulatory submission experience in key
markets (e.g. EU and USA.) Application of indirect comparison
methodology (e.g. Bayesian/Frequentist NMA and MAIC/STC
methodologies). Experience of performing adjustment for treatment
switching/cross-over within clinical trials (e.g. RPSFT and IPCW
methodology.). Analysis of health utility data including mapping
and value set application. Application of causal inference models
to clinical trial and RWE data. Experience of working with RWE
datasets and registries (e.g. Flatiron.). Why AstraZeneca? It's a
place to think differently - to find new ways of handling and
treating diseases. We are trusted and empowered to explore.
Ultimately, it's more than a job. We know that our work impacts
people with serious conditions, many of whom have no other
alternatives. That's what drives us - the potential to impact over
one billion patients worldwide. So, what's next If this sounds like
your next challenge - apply today We look forward to get to know
you better. Welcome to send us your application through our website
at your earliest convenience, but no later than 31st August 2022
For more information about these positions, please contact Owain
Saunders at Where can I find out more? Follow AstraZeneca on
Instagram: Read more about BioPharmaceuticals R&D: Please visit
our Biometrics landing page: AstraZeneca embraces diversity and
equality of opportunity. We are committed to building an inclusive
and diverse team representing all backgrounds, with as wide a range
of perspectives as possible, and harnessing industry-leading
skills. We believe that the more inclusive we are, the better our
work will be. We welcome and consider applications to join our team
from all qualified candidates, regardless of their characteristics.
We comply with all applicable laws and regulations on
non-discrimination in employment (and recruitment), as well as work
authorization and employment eligibility verification requirements.
AstraZeneca requires all US employees to be fully vaccinated for
COVID-19 but will consider requests for reasonable accommodations
as required by applicable law.
Keywords: AstraZeneca, Wilmington , Biometrics Team Leader/Senior Director - Global Medical Affairs/Payer Biometrics, Executive , Wilmington, Delaware
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