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Sr. Research Investigator / Principal Investigator, Pharmacology

Company: Incyte Corporation
Location: Wilmington
Posted on: October 15, 2020

Job Description:

Job Details Full-timeEstimated: $60,000 - $81,000 a year4 hours ago Qualifications - Western blot - Communication skills - Doctoral degree Full Job Description Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. Job Summary (Primary function) We are seeking a motivated individual to join our In Vivo Small Molecule Pharmacology group. This scientist will provide expertise and leadership for in vivo pharmacology studies that will aid in the discovery and advancement of novel tumor-directed and immuno-oncology based therapeutics. A successful candidate will be able to work independently to direct and conduct in vivo experiments in appropriate syngeneic, xenograft, PDX and humanized models. Incyte's culture of scientific rigor necessitates a candidate with a current and broad command of cancer biology and a willingness to work as part of cross-functional teams. Although this individual will be working to characterize the utility of novel agents, the candidate will also be expected to contribute to efforts with a number of established agents in our pipeline and selection of new targets. Summary of the Essential Functions of the Job Design or develop the appropriate in vivo model systems to answer key biological or pharmacological questions. This includes execution of antitumor efficacy studies, and studies to understand PK/PD relationships and drug mechanism of action. Perform ex vivo assessments of drug activity (e.g. Western blotting, MSD, HTRF, ELISA, flow cytometry) Demonstrate the ability to contribute to multiple projects, and collaborate with stakeholders from all relevant functions Research potential new drug targets and present to management for consideration as new drug discovery programs Manage energetic and enthusiastic bench scientists Minimum Requirements Ph.D. in Immunology, Cancer Biology, Pharmacology or related field Minimum of 3-5 years of postdoctoral training (Sr. Research Investigator) or 3-5 years of Pharma/Biotech experience (Principal Investigator) Experience with in vivo models of cancer Experience with handling and dosing of mice (i.v., i.p, s.c. and oral) is a plus Strong knowledge of cancer biology Expertise in a variety of ex-vivo assays; expertise in multi-color flow cytometry is a plus Excellent communication skills and a strong publication record Prior experience in managing bench scientists Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. We Respect Your Privacy Learn more at: The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate. During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here. You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is d, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable). Please contact if you have any questions or concerns or would like to exercise your rights. Show full job description Apply Now

Keywords: Incyte Corporation, Wilmington , Sr. Research Investigator / Principal Investigator, Pharmacology, Other , Wilmington, Delaware

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