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Principal Scientist, Biologics (Mass Spec)

Company: SGS
Location: West Chester
Posted on: May 25, 2023

Job Description:

Company Description

SGS is the global leader and innovator in inspection, verification, testing and certification services. Founded in 1878, SGS is recognized as the global benchmark in quality and integrity. With over 97,000 employees in 130 countries and operating a network of more than 2,400 offices and laboratories, we provide services to almost every industry by assuring quality and safety of products and services.

Job Description

The Principal Scientist, Biologics plays an active role as a member of the Technical Leadership for US Biologics. You will supervise, develop and mentor the Biologics Mass Spectrometry team, act as the subject matter expert, schedule projects and interface with clients. In addition, you will perform Mass Spec analyses of biologics such as LCMS.

  • Supervision of Biologics Mass Spectrometry Team
  • Provide technical input and support to the West Chester Customer Service Team as needed
  • Perform analytical studies on biologics utilizing primarily, but not solely, high-resolution LCMS in a fast-paced leading Contract Research Organization
  • Operate and maintain laboratory instrumentation required for cGMP analyses
  • Perform mass spectrometry analyses of biologics. These studies include, but are not limited to, protein Molecular weight analysis, peptide mapping, protein sequencing, post-translational modifications qualitative and quantitative analyses, and glycan structural analysis using primarily but not solely high-resolution mass spectrometry
  • Prepare chemical solutions and perform detailed and complex analytical procedures (e.g., digestions, purifications, buffer exchanges, etc.) following SOP and established test protocols
  • Write and review reports, protocols, and any documentation in relation to the performance of the work
  • Work closely with Quality Assurance to meet all necessary regulatory requirements

    • Ph.D. level scientist
    • 6+ years of experience in protein mass spectrometry in the biopharmaceutical industry (required)
    • 2+ years of supervisory experience
    • Strong hands-on experience with UPLC and high-resolution mass spectrometry applied to protein characterization, e.g. antibodies and/or therapeutic proteins
    • Expertise with de novo protein sequencing (manual and software-assisted data interpretation)
    • Industry cGMP experience preferred
    • Must be able to relocate to West Chester, PA where lab is located

      Additional Information

      SGS is an Equal Opportunity Employer, and as such we recruit, hire, train, and promote persons in all job classifications without regard to race, color, religion, sex, national origin, disability, age, marital status, sexual orientation, gender identity or expression, genetics, status as a protected veteran, or any other characteristics protected by law.

      To perform this job successfully, an individual must be able to perform each essential duty satisfactorily with or without reasonable accommodations. The requirements listed above are representative of the knowledge, skills, and/or abilities required.

      This job description should not be construed as an exhaustive statement of duties, responsibilities or requirements, but a general description of the job. Nothing contained herein restricts the company's rights to assign or reassign duties and responsibilities to this job at any time.

      If you are applying for a position within the United States and you have difficulty completing the on-line employment application because of a disability, please call 201-508-3149 for assistance and leave a message. You will receive a callback. Please note, this phone number is not for general employment information but is only for individuals who are experiencing difficulty applying for a position due to a disability.

Keywords: SGS, Wilmington , Principal Scientist, Biologics (Mass Spec), Other , West Chester, Delaware

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