Health Economics & Outcomes Research (HEOR) Senior Manager, Oncology

Company: Amgen
Location: Washington
Posted on: January 9, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Health Economics & Outcomes Research (HEOR) Senior Manager, Oncology What you will do Reporting to the HEOR Director, the HEOR Senior Manager is accountable for executing on the HEOR Book of Work, strategically aligned with the Access Strategy Lead (ASL), for one or several assets across the life cycle management The HEOR Book of Work comprises generating global-impact payer-relevant evidence, patient reported outcomes (PRO) and clinical outcomes assessment (COA) strategy, and evidence synthesis. Additionally, the HEOR Senior Manager is responsible to ensure delivery of global core materials to support Health Technology Assessment (HTA) submissions, including the Global Value Dossier (GVD) and economic models The HEOR Senior Manager role involves execution of deliverables, as well as engaging with internal and external stakeholders Responsibilities This role is global, with tactical execution. The HEOR Senior Manager must have experience in developing payer-relevant evidence generation, PRO/COA strategy, evidence synthesis and HTA requirements. The HEOR Senior Manager needs to engage effectively with internal customers to align and support the comprehensive HEOR plan, including the ASL, top-10 countries and cross-functional teams: Evidence Generation Team (EGT), Global Medical Affairs Team (GMAT), Center for Observational Research, Access and Use Evidence Generation team (AUEG), Global Biostatistical Sciences, US Value Marketing, Medical Value & Access. HEOR Book of Work: Payer-relevant evidence generation plan and execution of global-impact and United States local-impact studies. PRO/COA strategy Evidence synthesis Global core materials supporting HTA requirements, including Global Value Dossier (GVD) and economic models The HEOR Senior Manager will also engage with vendors and external experts to validate HEOR strategy and technical approach. The HEOR Senior Manager's main responsibilities include: Translating strategic objectives into concrete execution via HEOR project plan Maintaining strong working relationships with top-10 countries, particularly the United States Ensuring compliance with HTA dossier governance What we expect of you We are all different, yet we all use our unique contributions to serve patients. The technically astute professional we seek is a collaborative partner with these qualifications. Basic Qualifications: Doctorate degree and 2 years of health economics & outcomes research experience Or Master's degree and 4 years of health economics & outcomes research experience Or Bachelor's degree and 6 years of health economics & outcomes research experience Or Associates degree and 10 years of health economics & outcomes research experience Or High school diploma / GED and 12 years of health economics & outcomes research experience Preferred Qualifications: Health economics training (on the job or academic) Experience in writing research protocols and publications Experience in developing payer-relevant evidence, including real-world evidence Experience in designing PRO/COA strategy Experience in evidence synthesis (systematic literature reviews, indirect treatment comparisons and meta-analyses) Strategic and technical understanding of HTA requirements Experience in developing GVDs and AMCP dossiers Experience in developing economic models and predictive analytics Experience in the United States market Experience in influencing Access strategy with a HEOR lens Experience or interest in oncology therapeutic area Experience in Amgen products' specific therapeutic areas Experience with direct country HTA interactions Experience in early HTA engagement Ability to work with customers and colleagues based in different time zones Good presentation and communication skills Good interpersonal and soft skills Ability to influence without authority Understanding of clinical development process and regulatory evidence needs Ability to synthesize complex technical terms for non-technical audience Strategic thinking, while focusing on tactical execution What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Wilmington , Health Economics & Outcomes Research (HEOR) Senior Manager, Oncology, Science, Research & Development , Washington, Delaware