Research and Development Intern
Company: Legend Biotech
Location: Piscataway
Posted on: February 6, 2026
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Job Description:
Legend Biotech is a global biotechnology company dedicated to
treating, and one day curing, life-threatening diseases.
Headquartered in Somerset, New Jersey, we are developing advanced
cell therapies across a diverse array of technology platforms,
including autologous and allogenic chimeric antigen receptor
T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based
immunotherapy. From our three R&D sites around the world, we
apply these innovative technologies to pursue the discovery of
safe, efficacious and cutting-edge therapeutics for patients
worldwide. Legend Biotech entered into a global collaboration
agreement with Janssen, one of the pharmaceutical companies of
Johnson & Johnson, to jointly develop and commercialize
ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is
designed to combine the strengths and expertise of both companies
to advance the promise of an immunotherapy in the treatment of
multiple myeloma. Legend Biotech is seeking an Research &
Development Intern as part of the Novel Car Design team based in
Piscataway, NJ . Role Overview This internship will focus on
advancing our assessment of in vivo CAR T cell platform. This role
will provide hands-on experience in preclinical research and
adoptive cell therapy, providing the intern with the opportunity to
contribute to cutting-edge experiments and data analysis that drive
innovation in our research program. Key Responsibilities Assist in
the execution of laboratory experiments, including mammalian cell
culture, virus preparation, and immunological and biochemical
assays. Perform transfections for virus production and assess viral
titers using flow cytometry–based and ELISA-based assays. Conduct
PBMC transduction and perform immunoassays to screen and validate
candidates with improved efficacy and safety profiles. Perform
cytotoxicity assays, immunophenotyping, and cytokine analyses.
Maintain accurate and detailed records of experimental procedures,
data, and observations in laboratory notebooks. Analyze
experimental data and prepare summaries and reports for team
discussions. Collaborate with senior scientists and team members to
troubleshoot, optimize, and refine experimental protocols.
Candidate is encouraged to provide technical approaches and
troubleshooting strategies, but all experimental plans, data
interpretation, and project-related decisions require review and
approval by the manager or designated mentor. Decisions regarding
project scope, timelines, resource allocation, and overall
strategic direction remain under management oversight and are
aligned with overall business pipeline priorities. Requirements
Currently enrolled in, or recently graduated from, a Bachelor’s,
Master’s program in Biology, Biotechnology, Biochemistry,
Immunology, or a related field. Preferred to have basic laboratory
skills with some hands-on experience in mammalian cell culture
(immune cells) and other standard molecular biology techniques,
including flow cytometry, qPCR/ddPCR, ELISA, and immunoassays. The
ideal candidate would also have some cellular therapy experience.
Strong analytical and problem-solving, and organizational
abilities. Excellent written and verbal communication skills. Works
well independently while thriving in a collaborative team
environment. Prefer the candidate to have some knowledge of data
analysis tools such as Microsoft Office (Excel, Powerpoint),
Graphpad Prism, and potentially R and Python. Li-JR1 Li-Contract
Benefits Benefits include medical, dental, and vision insurance as
well as a 401(k) retirement plan with a company match that vests
fully on day one. We offer eight (8) weeks of paid parental leave
after just three (3) months of employment, and a paid time off
policy that includes vacation time, personal time, sick time,
floating holidays, and eleven (11) company holidays. Additional
benefits include flexible spending and health savings accounts,
life and AD&D insurance, short- and long-term disability
coverage, legal assistance, and supplemental plans such as pet,
critical illness, accident, and hospital indemnity insurance. We
also provide commuter benefits, family planning and care resources,
well-being initiatives, and peer-to-peer recognition programs;
demonstrating our ongoing commitment to building a culture where
our people feel empowered, supported, and inspired to do their best
work. Please note: These benefits are offered exclusively to
permanent full-time employees. Contract employees are not eligible
for benefits through Legend Biotech. EEO Statement It is the policy
of Legend Biotech to provide equal employment opportunities without
regard to actual or perceived race, color, creed, religion,
national origin, ancestry, citizenship status, age, sex or gender
(including pregnancy, childbirth, related medical conditions and
lactation), gender identity or gender expression (including
transgender status), sexual orientation, marital status, military
service and veteran status, disability, genetic information, or any
other protected characteristic under applicable federal, state or
local laws or ordinances. Employment is at-will and may be
terminated at any time with or without cause or notice by the
employee or the company. Legend may adjust base salary or other
discretionary compensation at any time based on individual, team,
performance, or market conditions. For information related to our
privacy policy, please review: Legend Biotech Privacy Policy.
Keywords: Legend Biotech, Wilmington , Research and Development Intern, Science, Research & Development , Piscataway, Delaware
