Observational Research Manager

Company: Amgen
Location: Washington
Posted on: February 6, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Observational Research Manager What you will do Lets do this. Lets change the world. Are you searching for a new, dynamic opportunity working with multiple teams to generate real world evidence supporting a wide variety of business needs? If so, we invite you to explore Amgens Center for Observational Research. With a constantly increasing demand for information from regulatory and reimbursement agencies, observational research (OR) has become a critical component in drug development and commercialization. Amgens Center for Observational Research (CfOR) partners with internal and external teams to generate real world evidence for multiple stakeholders across the product lifecycle. CfOR contributes evidence regarding the frequency and distribution of disease or the clinical burden of disease, the natural history or clinical course of disease, the design of clinical trials, cost and utilization patterns and the safety and effectiveness of interventions. In this vital role, the Observational Research Manager will be a key member of the Clinical Program Design team within CfORs Data and Analytic Center (DAC) and will be responsible for generating insights and building collaborations and capabilities to advance the use of real world evidence for clinical program design and planning. Preferably, CfOR Managers will be located on the Amgen corporate campus in Thousand Oaks, CA, but remote working opportunities may also be available. Key activities of a CfOR Manager include: Design and execute RWE studies to support evidence generation for clinical trial design and planning, such as identifying the appropriate patient population, assessing the burden and distribution of disease and disease phenotyping Execute and manage research projects involving literature reviews and the analysis of multiple types of data including medical claims, electronic health records and prospective observational cohort studies. Contribute to the development and implementation of innovative analytic methods, capabilities and tools to enable rapid, scalable and reproducible RWE Communicate significant scientific information to a variety of audiences What we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Research Manager with these qualifications. Basic Qualifications: Doctorate degree or Master's degree and 3 years of related research and scientific experience or Bachelor's degree and 5 years of related research and scientific experience or Bachelor's degree and 10 years of related research and scientific experience or High School diploma / GED and 12 years of related research and scientific experience Preferred Qualifications: Doctorate in Epidemiology or other subject with high observational research content. Experience in the design, execution and analysis of observation research studies within Pharmaceutical and/or Public Health settings. Experience in research to support drug development. Experience working with secondary data systems including administrative claims, EMR and registries. Experience in observational research project planning and management. Excellent communication, presentation and interpersonal skills. Proven experience working with and leading multi-disciplinary teams. What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, Wilmington , Observational Research Manager, Science, Research & Development , Washington, Delaware